Over 2/3 of all star formation in the Universe occurs in gas-rich, super-high pressure clumpy galaxies in the epoch of redshift z~1-3. However, because these galaxies are so distant, we are limited in the information available to study the properties of star formation and gas in these systems. I will present results using a sample of extremely rare, nearby galaxies (from the DYNAMO survey and the new DUVET survey) that are very well matched in gas fraction, kinematics, structure and morphology to z=1-2 main-sequence galaxies. We use these galaxies as laboratories to study the processes inside galaxies in the dominate mode of star formation in the Universe. In this talk I will report on results that are aimed at testing models of star formation in galaxies. Feedback regulated star formation theories aim to explain properties like the velocity dispersion of disks, the relationship between gas and star formation and the vertical scale height of thin disks in galaxies. I will make direct comparisons to the expectations of these theories to our observations. I will discuss my group's very recent efforts to connect the regulation of gas via outflows to the picture of how galaxies maintain their star formation rates and positions in Kennicutt-Schmidt relationship. Finally, I will argue that the next step we need is observations of the multiphase ISM and outflows, and discuss the new large VLT program GECKOS that is intended to do just that. Those unable to attend the colloquium in person are invited to participate online through Zoom (Meeting ID: 942 0262 2849, passcode 792771) using the link: https://zoom.us/j/94202622849?pwd=dGlPQXBiUytzY1M2UE5oUDRhbzNOZz09 Prof. Fisher will be based at the ARI institute for her visit to Heidelberg and will be available for meetings by arrangement with her host, Kathryn Kreckel (kathryn.kreckel@uni-heidelberg.de).